Coenzyme Q10 or "ubiquinone" is a fat-soluble molecule that plays an essential role in the proper functioning of the mitochondria, the intracellular organelles that act as precious "power plants" of our cells. Mitochondria play a central role in the cellular respiration process, through which they produce the energy contained in food, transformed and accumulate it in molecules of adenosine triphosphate (ATP), preserved and ready for use, which we find present throughout the body and in abundance in the heart, liver, kidneys and pancreas.
Coenzyme Q10 is a powerful antioxidant that protects cell membranes from oxidative damage, helping to strengthen the immune system, which favors the physiological function of the heart and its protection, intervening in the maintenance of neurocerebral health, in the maintenance of male fertility, in counteracting consequences of diabetic states, and has an interesting skin "anti-aging" action. With age, the concentration of coenzyme Q10 decreases, resulting in a decrease in both energy efficiency and antioxidant action, thus favoring the aging processes. Lower levels of this enzyme are also found in the presence of heart disease, diabetes, some neurodegenerative pathologies, and in various other pathologies, but lower Q10 values are also found in athletes, in particular in endurance sports.
Coenzyme Q10 is well tolerated and generally does not produce any side effects, but beware that it could reduce the effectiveness of some chemotherapy drugs, antihypertensive drugs and warfarin.
Coenzyme Q10. Monograph. Altern Med Rev. 2007 Jun;12(2):159-68. PMID: 17604461.
Zozina VI, Covantev S, Goroshko OA, Krasnykh LM, Kukes VG. Coenzyme Q10 in Cardiovascular and Metabolic Diseases: Current State of the Problem. Curr Cardiol Rev. 2018;14(3):164-174. doi: 10.2174/1573403X14666180416115428. PMID: 29663894; PMCID: PMC6131403.
Quinzii CM, DiMauro S, Hirano M. Human coenzyme Q10 deficiency. Neurochem Res. 2007 Apr-May;32(4-5):723-7. doi: 10.1007/s11064-006-9190-z. Epub 2006 Nov 10. PMID: 17094036; PMCID: PMC1832150.
Ho CC, Tseng CY, Chen HW, Chiu YW, Tsai MC, Chang PS, Lin PT. Coenzyme Q10 status, glucose parameters, and antioxidative capacity in college athletes. J Int Soc Sports Nutr. 2020 Jan 10;17(1):5. doi: 10.1186/s12970-020-0334-3. PMID: 31924223; PMCID: PMC6954618.
Jafari M, Mousavi SM, Asgharzadeh A, Yazdani N. Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews. Indian Heart J. 2018 Jul;70 Suppl 1(Suppl 1):S111-S117. doi: 10.1016/j.ihj.2018.01.031. Epub 2018 Jan 31. PMID: 30122240; PMCID: PMC6097169.
Suárez-Rivero JM, Pastor-Maldonado CJ, de la Mata M, Villanueva-Paz M, Povea-Cabello S, Álvarez-Córdoba M, Villalón-García I, Suárez-Carrillo A, Talaverón-Rey M, Munuera M, Sánchez-Alcázar JA. Atherosclerosis and Coenzyme Q10. Int J Mol Sci. 2019 Oct 20;20(20):5195. doi: 10.3390/ijms20205195. PMID: 31635164; PMCID: PMC6834161.
Zhang X, Shi Z, Liu Q, Quan H, Cheng X. Effects of coenzyme Q10 intervention on diabetic kidney disease: A systematic review and meta-analysis. Medicine (Baltimore). 2019 Jun;98(24):e15850. doi: 10.1097/MD.0000000000015850. PMID: 31192915; PMCID: PMC6587473.
Ben-Meir A, Burstein E, Borrego-Alvarez A, Chong J, Wong E, Yavorska T, Naranian T, Chi M, Wang Y, Bentov Y, Alexis J, Meriano J, Sung HK, Gasser DL, Moley KH, Hekimi S, Casper RF, Jurisicova A. Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell. 2015 Oct;14(5):887-95. doi: 10.1111/acel.12368. Epub 2015 Jun 26. PMID: 26111777; PMCID: PMC4568976.
60 capsules Nutrition facts Daily dose (1 capsule) Servings per container: 60 Per daily dose (1 capsule)
Ingredients: coenzyme Q10, capsule (glazing agent: hydroxypropyl methyl cellulose), bulking agent: cellulose; anti-caking agents: magnesium salts of fatty acids, silicon dioxide.
How to use: take 1 capsule a day with water.
WARNINGS: do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of young children. Keep in a cool and dry place. Avoid exposure to heat sources and sunlight.